This just makes the game "pop" a lot more, darks are a bit darker, and everything is a bit more colorful so the game looks less gray, I personally think it's better for the eyes to be honest.
This is a preset I made myself because the game looked so washed out, it adds a lot of depth and color to the game, makes the game's mood much better, and more realistic imo.Yes, it works with Iceborne, as updates don't affect how reshade works.